Nexus Infection Wiki & Guide

Place a bed anywhere in your world, and strange visitors will begin spawning near your base at night to spread the corruption. The infection will gradually expand from there, turning terrain into dead blocks and spawning alien plants.

You can slow or contain the spread by crafting and placing wards around your base, which create protected zones. However, the infection cannot be completely stopped—only managed and defended against.

Tumors are infected ground blocks that rapidly corrupt the surrounding terrain into dead blocks and spawn alien plants and red fog. When a tumor finishes corrupting the land above it, a massive underground hive generates beneath.

Hives generate automatically underground when a tumor finishes corrupting the surface above it. You can identify them by mining down through heavily infected areas or exploring deep underground in corrupted regions.

Find a Hive Root inside an underground hive and use a Nexium Heart on it to summon the Torment Root mini-boss. Defeat it to obtain the Nexium Tentacle, which lets you instantly break infected blocks.

Overgrown Castles spawn naturally in savannas and swamps as corrupted structures. They contain locked chests that require a Radiant Key to open and hold valuable loot.

Friendly animals are mutated by the plague into hostile undead monsters that attack other creatures and spread the sickness further. These mutated mobs are more dangerous than normal hostile mobs.

Focus on collecting Heartlens and special cores found inside hives, as these are essential materials for crafting wards and other protective items. The Nexium Heart is also crucial for summoning the Torment Root boss.

The Nexium Tentacle makes mining infected blocks much faster, which is helpful but not strictly required. However, it becomes increasingly useful as the infection spreads and you need to clear corrupted terrain.

Yes—if left unchecked, the spreading corruption will eventually consume your base and turn it into dead blocks. Placing wards around your base creates protected zones that slow or prevent this spread.